(AGENPARL) – BARCELONA lun 22 maggio 2023
Targeted protein degradation as a therapeutic strategy – the focus of the 39th Barcelona BioMed Conference
EnzoAndres.Crisosto
Mon, 05/22/2023 – 09:03
Targeted protein degradation uses different types of “degrading” drugs (degraders) to force proximity between a target protein (for example, a mutated protein that contributes to the development of a disease) and the cellular machinery that directs protein degradation. By inducing such proximity, the target proteins are marked for destruction by the cellular proteasome.
Fonte/Source: https://www.irbbarcelona.org/en/news/institutional/targeted-protein-degradation-therapeutic-strategy-focus-39th-barcelona-biomed