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TARGETING NSP1 PROTEIN COULD BE A PATHWAY FOR COVID-19 THERAPY

Redazione
(AGENPARL) – DALLAS (TEXAS), mar 16 febbraio 2021 The virus SARS-CoV-2 targets the RNA export pathway to block host RNA in the nucleus and promote infection. Illustration by Angela Diehl DALLAS – Feb. 16, 2021 – A study that identifies how a coronavirus protein called Nsp1 blocks the activity of genes......
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UNCOVERING THE INTERACTIONS DRIVING CAROTENOID BINDING IN LIGHT-HARVESTING COMPLEXES

Redazione
(AGENPARL) – LONDON (UNITED KINGDOM), lun 15 febbraio 2021 Carotenoids are essential constituents of plant light-harvesting complexes (LHCs), being involved in protein stability, light harvesting, and photoprotection. Unlike chlorophylls, whose binding to LHCs is known to require coordination of the central magnesium, carotenoid binding relies on weaker intermolecular interactions (such......
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RESTRICTED BINDING OF A MODEL PROTEIN ON C3N4 NANOSHEETS SUGGESTS AN ADEQUATE BIOCOMPATIBILITY OF THE NANOMATERIAL

Redazione
(AGENPARL) – LONDON (UNITED KINGDOM), sab 13 febbraio 2021 Recently, C3N4, a carbon nitride nanomaterial, has attracted great attention in many scientific fields due to its outstanding properties. Specifically, this nanomaterial has displayed non- or low-toxicity in biological systems suggesting its excellent biocompatibility and biosafety. Nevertheless, few studies address the......
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NEW INSIGHT INTO PROTEIN STRUCTURES THAT COULD TREAT HUNTINGTON’S DISEASE

Redazione
(AGENPARL) – WORCESTER (MASSACHUSETTS), sab 13 febbraio 2021 (University of Groningen) In Huntington’s disease, a faulty protein aggregates in brain cells and eventually kills them. Such protein aggregates could, in principle, be prevented with a heat shock protein. However, it is not well known how these proteins interact with the......
Agenparl English Educazione Scienza e Tecnologia Social Network

MEDICATION-BASED STARVATION OF CANCER CELLS

Redazione
(AGENPARL) – MüNCHEN (BAYERN), ven 12 febbraio 2021 Previous studies have shown that IMiDs bind to a protein called cereblon, which results in the malfunction of a protein complex on the surface of tumor cells, thus inhibiting tumor growth. A research team led by Prof. Florian Bassermann and Vanesa Fernández......
Agenparl English Educazione Scienza e Tecnologia Social Network

DIGESTIVE CHARACTERISTICS AND PEPTIDE RELEASE FROM WHEAT EMBRYO FUNCTIONAL PROTEINS IN VITRO

Redazione
(AGENPARL) – LONDON (UNITED KINGDOM), gio 11 febbraio 2021 Data about the digestion and metabolism of wheat embryo functional proteins (WEFP) in the gastrointestinal tract is currently lacking. The aim of this study was to utilize a simulated gastrointestinal digestion (SGID) scheme in vitro in order to explain the protein......
Agenparl English Educazione Salute Scienza e Tecnologia Social Network

HOW THE 3-D STRUCTURE OF EYE-LENS PROTEINS IS FORMED

Redazione
(AGENPARL) – WORCESTER (MASSACHUSETTS), gio 11 febbraio 2021 (Goethe University Frankfurt) Chemical bonds within the eye-lens protein gamma-B crystallin hold the protein together and are therefore important for the function of the protein within the lens. Contrary to previous assumptions, some of these bonds, called disulphide bridges, are already formed......
Agenparl English Educazione Scienza e Tecnologia Social Network

PLANT STEROL ESTER OF α-LINOLENIC ACID AMELIORATES HIGH-FAT DIET-INDUCED NONALCOHOLIC FATTY LIVER DISEASE IN MICE: ASSOCIATION WITH REGULATING MITOCHONDRIAL DYSFUNCTION AND OXIDATIVE STRESS VIA ACTIVATING AMPK SIGNALING

Redazione
(AGENPARL) – LONDON (UNITED KINGDOM), mer 10 febbraio 2021 The present study was designed to explore the beneficial mitochondrial effects and anti-oxidative activities of plant sterol ester of α-linolenic acid (PS-ALA) through AMP-activated protein kinase (AMPK) signaling in the treatment of nonalcoholic fatty liver disease (NAFLD) using in vivo and......
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FUNCTION IDENTIFIED OF ‘MYSTERY PROTEIN’ THAT KILLS HEALTHY BRAIN CELLS OF PEOPLE WITH PARKINSON’S

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(AGENPARL) – CAMBRIDGE (ENGLAND), mer 10 febbraio 2021 A study published in Nature Communications presents new evidence about what a key protein called alpha-synuclein actually does in neurons in the brain. Dr Giuliana Fusco from the University of Cambridge, and lead author of the paper, said: “This study could unlock......
Agenparl English Educazione Salute Scienza e Tecnologia Social Network

FUNCTION IDENTIFIED OF ‘MYSTERY PROTEIN’ THAT KILLS BRAIN CELLS OF PEOPLE WITH PARKINSON’S

Redazione
(AGENPARL) – WORCESTER (MASSACHUSETTS), mer 10 febbraio 2021 IMAGE: 3D illustration showing neurons containing Lewy bodies small red spheres which are deposits of proteins accumulated in brain cells that cause their progressive degeneration. view more  Credit: Kateryna Kon via Shutterstock A study published in Nature Communications today (Wednesday 10 February) presents......

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