(AGENPARL) – lun 06 marzo 2023 [Screenshot (124).png]
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Resistance of Salmonella and Campylobacter to commonly used antimicrobials is frequently observed in humans and animals, reveals a report issued today by the European Centre for Disease Prevention and Control (ECDC) and the European Food Safety Authority (EFSA). However, simultaneous resistance to critically important antimicrobials for humans was generally detected at low levels, except for some Salmonella types and Campylobacter coli in several countries.
“Antimicrobial resistance is one of the greatest threats we face worldwide, affecting humans, animals, and the environment. Working together remains key to tackling this complex problem. In our work, we embody the One Health approach, recognising the close links and interdependency of the health of humans, animals, plants, and the wider environment,” said ECDC and EFSA chief scientists Mike Catchpole and Carlos Das Neves in a joint statement.
There were encouraging trends in several countries, where an increasing proportion of bacteria from food-producing animals was susceptible to all tested antimicrobials. Moreover, the prevalence of Extended-spectrum Beta-lactamases (ESBLs) and AmpC beta-lactamases (AmpC) producing E. Coli is decreasing.
A decline in the resistance of Salmonella to ampicillin and tetracycline was also observed in humans in several countries over the period 2013–2021. This was particularly evident in S.?Typhimurium, a type of Salmonella commonly associated with pigs and calves, which is often multidrug-resistant. Data also show decreasing trends in resistance of Campylobacter jejuni to erythromycin in humans and broilers.
This type of antimicrobial is very important in the treatment of campylobacteriosis.
However, the report also shows an increasing trend over the same period in the resistance of S. Enteritidis and C.?jejuni to ciprofloxacin in humans. S.?Enteritidis and C. jejuni cause most cases of salmonellosis and campylobacteriosis infections in humans.
Similar trends were observed in C. jejuni from broilers between 2009 and 2020, where resistance to ciprofloxacin increased in several countries. The level of ciprofloxacin resistance in Campylobacter is now so high that this antimicrobial can no longer be recommended in the treatment of severe Campylobacter infections in humans.
Resistance of E. coli?to carbapenem remains rare in food-producing animals and humans. Since carbapenems are a class of last-resort antimicrobials, any findings showing resistance to these in zoonotic bacteria are a concern. Therefore, resistance to carbapenem needs to be kept monitored and investigated.
EFSA is also publishing several interactive communication tools:
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