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targeting

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COMBINATION TARGETING OF ‘PLATELETS + FIBRIN’ ENHANCES CLOT ANCHORAGE EFFICIENCY OF NANOPARTICLES FOR VASCULAR DRUG DELIVERY

Redazione
(AGENPARL) – LONDON (UNITED KINGDOM), gio 17 settembre 2020 Occlusive thrombosis is a central pathological event in heart attack, stroke, thromboembolism etc. Therefore, pharmacological thrombolysis or anticoagulation is used in treating these diseases. However, systemic administration of such drugs causes hemorrhagic side-effects. Therefore, there is significant clinical interest in strategies......
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POLY-γ-GLUTAMIC ACID DERIVED NANOPOLYPLEXES FOR UP-REGULATION OF GAMMA-GLUTAMYL TRANSPEPTIDASE TO AUGMENT TUMOR ACTIVE TARGETING AND ENHANCE SYNERGISTIC ANTITUMOR THERAPY BY REGULATING INTRACELLULAR REDOX HOMEOSTASIS

Redazione
(AGENPARL) – LONDON (UNITED KINGDOM), gio 10 settembre 2020 Active targeting strategy had achieved inspiring progress for drug accumulation in tumor therapy, however, the insufficient expression level of many potential receptors posed challenges for drug delivery. Poly-γ-glutamic acid (γ-pGluA), a naturally occurring anionic biopolymer, showed high affinity with Tumor-associated gamma-glutamyl......
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CHARACTERIZATION AND TARGETING ABILITY EVALUATION OF CELL-PENETRATING PEPTIDE LYP-1 MODIFIED ALGINATE-BASED NANOPARTICLES

Redazione
(AGENPARL) – LONDON (UNITED KINGDOM), ven 04 settembre 2020 Doxorubicin hydrochloride (DOX) shows a powerful treatment effect on breast cancer. However, for its indiscriminate distribution after systemic administration, the therapeutic response of DOX will reduce and even result in serious adverse reactions during the long-term administration. To achieve better treatment,......
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TUNISIA MONETARY POLICY SINCE THE ARAB SPRING: THE FALL OF THE EXCHANGE RATE ANCHOR AND RISE OF INFLATION TARGETING

Redazione
(AGENPARL) – WASHINGTON (DC), ven 21 agosto 2020 Author/Editor: Nicolas End ; Mariam El Hamiani Khatat ; Rym Kolsi Publication Date: August 21, 2020 Electronic Access: Free Download. Use the free Adobe Acrobat Reader to view this PDF file Disclaimer: IMF Working Papers describe research in progress by the author(s)......
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BIOINSPIRED β-GLUCAN MICROCAPSULES DELIVER FK506 TO LYMPH NODES FOR TREATMENT OF CARDIAC ALLOGRAFT ACUTE REJECTION

Redazione
(AGENPARL) – LONDON (UNITED KINGDOM), mer 29 luglio 2020 Lymph node (LN)-targeted delivery exhibits enormous potential to improve the treatment efficacy of immunosuppressants for transplantation. However, current strategies are still limited by the inefficiency of delivery by passive targeting, the high cost of antibody-mediated active targeting, as well as poor......

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