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Agenparl English Educazione Salute Scienza e Tecnologia Social Network

BUILDING BRIDGES: PARP ENZYMES BRING BROKEN DNA TOGETHER

Redazione
(AGENPARL) – WORCESTER (MASSACHUSETTS), mer 16 settembre 2020 Scientists at St. Jude Children’s Research Hospital have identified the structure of double-strand DNA break repair by PARP enzymes. The findings show that PARP2 can bridge the gap, bringing two broken DNA ends together. The study also provides insight into the mechanisms......
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THE ROLE OF ALLOYED STRONTIUM IN THE MICROSTRUCTURES AND ALKALINE ELECTROCHEMISTRY OF MG–5AL–4SN ALLOYS

Redazione
(AGENPARL) – LONDON (UNITED KINGDOM), mer 16 settembre 2020 In this study, strontium is used as an alloying element for improving the pitting resistance of Mg–5Al–4Sn based alloys in an alkaline solution. Potentiodynamic polarization measurements suggest that the addition of strontium increases the robustness of the pitting resistance as a......
Agenparl English Educazione Social Network

TRICHODERMA [ELECTRONIC RESOURCE] : HOST PATHOGEN INTERACTIONS AND APPLICATIONS / ANIL K. SHARMA, PRATIBHA SHARMA, EDITORS.

Redazione
(AGENPARL) – LETHBRIDGE, ALBERTA, CANADA), mar 15 settembre 2020 Description 1 online resource (331 pages). Note Description based upon print version of record. Contents Intro — Foreword — Preface — Contents — Editors and Contributors — Abbreviations — Chapter 1: Can We Define an Experimental Framework to Approach the Genetic......
Agenparl English Educazione Scienza e Tecnologia Social Network

SENSING-RANGE-TUNABLE PRESSURE SENSORS REALIZED BY SELF-PATTERNED-SPACER DESIGN AND VERTICAL CNT ARRAYS EMBEDDED IN PDMS

Redazione
(AGENPARL) – LONDON (UNITED KINGDOM), gio 10 settembre 2020 A pressure sensor design suitable for a broad sensing range with high sensitivity and good stability is highly desirable for the detection of various pressures and meeting the requirements of different applications. Herein, we report sensing-range-tunable piezoresistive pressure sensors realized by......
Agenparl English Educazione Salute Scienza e Tecnologia Social Network

CAFFEINE SHOT DELIVERS WAKEUP CALL ON ANTIFUNGAL DRUG RESISTANCE

Redazione
(AGENPARL) – WORCESTER (MASSACHUSETTS), mer 09 settembre 2020 The management of fungal infections in plants and humans could be transformed by a breakthrough in understanding how fungi develop resistance to drugs. It was previously thought that only mutations in a fungi’s DNA would result in antifungal drug resistance. Current diagnostic......
Agenparl English Educazione Scienza e Tecnologia Social Network

NEW METHOD COULD HELP TO FIND THE BEST TREATMENT FOR A PEDIATRIC CANCER

Redazione
(AGENPARL) – BARCELONA (SPAIN), mer 09 settembre 2020 A study led by IBEC researchers from the Nanobioengineering Group in collaboration with other research institutes and hospitals in Barcelona, uses a functional predictive biomarker to anticipate the effect of treatments against rhabdomyosarcoma, the most common soft-tissue cancer affecting childhood and adolescence.This......
Agenparl English Educazione Scienza e Tecnologia Social Network

OVERCOMING THERAPEUTIC FAILURE IN OSTEOSARCOMA VIA APATINIB-ENCAPSULATED HYDROPHOBIC POLY (ESTER AMIDE) NANOPARTICLES

Redazione
(AGENPARL) – LONDON (UNITED KINGDOM), lun 07 settembre 2020 Anti-angiogenesis tyrosine kinase inhibitors (TKIs) have been proved to be effective in prolonging progression-free survival in advanced osteosarcoma. However, osteosarcoma stem-like cells persist long term and ultimately cause disease recurrence and therapy resistance. Here, we reveal that inefficient accumulation of Apatinib,......
Agenparl English Educazione Scienza e Tecnologia Social Network

TWO RUTHENIUM POLYPYRIDYL COMPLEXES FUNCTIONALIZED WITH THIOPHEN: SYNTHESIS AND ANTIBACTERIAL ACTIVITY AGAINST STAPHYLOCOCCUS AUREUS

Redazione
(AGENPARL) – LONDON (UNITED KINGDOM), ven 04 settembre 2020 Two ruthenium polypyridyl complexes: [Ru(dmb)2(ETPIP)](ClO4)2 (Ru(Ⅱ)-1) and [Ru(phen)2(ETPIP)](ClO4)2 (Ru(Ⅱ)-2) (dmb=4,4′-dimethyl-2,2′-bipyridine, phen=1,10-phenanthroline, ETPIP=2-(4-(thiophen-2-ylethynyl)phenyl)-1H-imidazo[4,5-f] [1,10]phenanthroline), have been synthesized and characterized. Their antimicrobial activities against S. aureus were assessed. Both complexes Ru(II)-1, Ru(II)-2 show meaningful activity against Staphylococcus aureus and the lead complexes of......
Agenparl English Educazione Social Network

ANTIRETROVIRAL THERAPY FAILS TO TREAT ONE-THIRD OF HIV PATIENTS IN MALAWI HOSPITAL

Redazione
(AGENPARL) – CAMBRIDGE (ENGLAND), gio 03 settembre 2020 The observational study involving more than 1,300 people was led by the London School of Hygiene & Tropical Medicine (LSHTM), University of Malawi College of Medicine and University of Cambridge. It found most patients admitted to hospital knew their HIV status, and......
Agenparl English Educazione Salute Scienza e Tecnologia Social Network

NEWLY IDENTIFIED GENE GRANTS TOMATOES RESISTANCE TO BACTERIAL SPECK DISEASE

Redazione
(AGENPARL) – WORCESTER (MASSACHUSETTS), gio 03 settembre 2020 IMAGE: Bacterial speck disease, which reduces both fruit yield and quality, has been a growing problem in tomatoes over the last five years. view more  Credit: Greg Martin Bacterial speck disease, which reduces both fruit yield and quality, has been a growing problem......

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