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mitochondria

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SCIENTISTS DEVELOP HIGH-THROUGHPUT MITOCHONDRIA TRANSFER DEVICE

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(AGENPARL) – WORCESTER (MASSACHUSETTS), mar 29 dicembre 2020 Scientists from the UCLA Jonsson Comprehensive Cancer Center have developed a simple, high-throughput method for transferring isolated mitochondria and their associated mitochondrial DNA into mammalian cells. This approach enables researchers to tailor a key genetic component of cells, to study and potentially......
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UCLA SCIENTISTS DEVELOP HIGH-THROUGHPUT MITOCHONDRIA TRANSFER DEVICE

Redazione
(AGENPARL) – WORCESTER (MASSACHUSETTS), mar 29 dicembre 2020 LOS ANGELES — Scientists from the UCLA Jonsson Comprehensive Cancer Center have developed a simple, high-throughput method for transferring isolated mitochondria and their associated mitochondrial DNA into mammalian cells. This approach enables researchers to tailor a key genetic component of cells, to......
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MATRIX TARGETED FLUORESCENT PROBE TO MONITOR MITOCHONDRIAL DYNAMICS

Redazione
(AGENPARL) – LONDON (UNITED KINGDOM), mer 23 dicembre 2020 Mitochondria are indispensable organelle for energy production and regulation of cellular metabolism. The structural and functional alterations to mitochondria instigate pathological conditions of cancer, aging-associated and neurodegenerative disorders. The normal functioning of mitochondria is maintained by quality control mechanisms involving dynamic......
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AUTOPHAGY-DEFICIENT ARABIDOPSIS MUTANT ATG5, WHICH SHOWS ULTRAVIOLET-B SENSITIVITY, CANNOT REMOVE ULTRAVIOLET-B-INDUCED FRAGMENTED MITOCHONDRIA

Redazione
(AGENPARL) – LONDON (UNITED KINGDOM), sab 28 novembre 2020 Mitochondria damaged by ultraviolet-B radiation (UV-B, 280–315 nm) are removed by mitophagy, a selective autophagic process. Recently, we demonstrated that autophagy-deficient Arabidopsis thaliana mutants exhibit a UV-B-sensitive phenotype like that of cyclobutane pyrimidine dimer (CPD)-specific photolyase (PHR1)-deficient mutants. To explore the......
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SCIENTISTS DEVELOP NEW GENE THERAPY FOR EYE DISEASE

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(AGENPARL) – WORCESTER (MASSACHUSETTS), gio 26 novembre 2020 IMAGE: A fluorescent microscope image with mitochondria highlighted in gold. This healthy cell shows a highly elaborate and well-connected network of mitochondria. view more  Credit: Professor Jane Farrar and Dr Daniel Maloney, Trinity College Dublin Scientists from Trinity College Dublin have developed a......
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INNOVATIVE MACHINE-LEARNING APPROACH FOR FUTURE DIAGNOSTIC ADVANCES IN PARKINSON’S DISEASE

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(AGENPARL) – WORCESTER (MASSACHUSETTS), gio 12 novembre 2020 Parkinson’s disease (PD) is the second most common neurodegenerative disease, with patient numbers being expected to double worldwide in the next 20 years. The detailed molecular and cellular mechanisms underlying its pathogenesis remains unclear, although recent evidence has pointed towards the role......
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NOT_RESEARCHERS REVEAL THE EVOLUTIONARY EVENTS LEADING TO THE CREATION OF EUKARYOTIC CELLS

Redazione
(AGENPARL) – BARCELONA (SPAIN), ven 30 ottobre 2020 Mitochondrial acquisition occurred in a scenario of increasing complexity (Image: IRB Barcelona, Utrecht University). One of the most important and puzzling events in the evolution of life has been the origin of the first complex eukaryotic cells. Almost all lifeforms that we......

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