(AGENPARL) – Mon 08 December 2025 No images? Click here https://hq_who_departmentofcommunications.cmail20.com/t/d-e-gtiikky-iitylyihjr-k/
Monday, 8 December 2025
SITUATION REPORT
Multi-country outbreak of mpox, External situation report #60 – 8 December 2025 [https://www.who.int/publications/m/item/multi-country-outbreak-of-mpox–external-situation-report–60—8-december-2025]
https://www.who.int/publications/m/item/multi-country-outbreak-of-mpox–external-situation-report–60—8-december-2025
Overview
This is the 60th situation report for the multi-country outbreak of mpox, which provides details on the global epidemiological situation for mpox, including an update on the epidemiological situation with data on the global situation as of 31 October 2025, in Africa as of 23 November and the operational response updates as of 24 November 2025.
Highlights
• All clades of the monkeypox virus (MPXV) continue to circulate. When mpox outbreaks are not rapidly contained and human-to-human transmission is not interrupted, there is a risk of sustained community transmission.
• In October 2025, 44 countries, across all WHO regions, reported a total of 2501 new confirmed mpox cases, including 12 deaths (case fatality ratio [CFR] 0.5%). About 75% of these cases were reported in the African Region. All regions, apart from the South-East Asia Region observed a decline in confirmed cases in October, compared to September 2025.
• Twenty-one countries in Africa have reported active transmission of mpox in the last six weeks (12 October – 23 November 2025), with 1734 confirmed cases, including 10 deaths (CFR 0.6%) reported during this period. Countries reporting the highest number of cases in this period are the Democratic Republic of the Congo, Liberia, Ghana, Kenya and Uganda; with all of them showing a downward trend in cases in recent weeks.
• One country, Mali, has reported mpox for the first time. The case reported a recent history of travel to Guinea. Genomic sequencing analysis is ongoing to determine the MPXV clade.
• Greece has reported detection of clade Ib MPXV for the first time.
• New imported cases of mpox due to clade Ib MPXV detected among travellers have been reported in Belgium, Germany, Greece, and the United Kingdom of Great Britain and Northern Ireland.
• Since the last report, at least 15 cases of mpox due to clade Ib MPXV have been detected among individuals who self-identify as men who have sex with men.
• Outside Africa, local transmission of clade Ib MPXV has been occurring in Italy, the Netherlands, Portugal and Spain, the United States of America and Malaysia.
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