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Friday, 27 June 2025
SITUATION REPORT
Multi-country outbreak of mpox, External situation report #54 – 27 June 2025 [https://www.who.int/publications/m/item/multi-country-outbreak-of-mpox–external-situation-report–54—27-june-2025]
This is the 54th situation report for the multi-country outbreak of mpox, which provides details on the global epidemiological situation for mpox with data as of 31 May 2025, including an update on the epidemiological situation for mpox in Africa, with data as of 22 June 2025, and the operational response updates as of 26 June 2025.
Highlights
• In May 2025, a total of 6823 confirmed mpox cases and 16 deaths (Case Fatality Ratio: 0.2%) were reported from 49 countries across all WHO regions.
• The majority of mpox cases continue to be reported from the WHO African Region, with 18 countries currently experiencing active ongoing transmission.
• Since the last report, Ethiopia and Italy have reported their first cases of mpox due to clade Ib monkeypox virus (MPXV). In addition, North Macedonia, the Republic of the Congo, and Togo have reported their first cases of mpox clade IIb MPXV. Albania has reported its first mpox case, and genomic sequencing analysis is underway to determine the clade.
• Community transmission of clade Ib MPXV remains limited to countries in Central and East Africa.
• In Sierra Leone, the epidemic trend is consistently declining, although recent data should be interpreted with caution due to reporting delays.
• Eleven African countries have received mpox vaccines, of which seven have started mpox vaccination. More than 731 000 doses of the MVA-BN vaccine have been administered to date.
• WHO has updated its guideline on clinical management and infection prevention and control for mpox.
• The WHO Director-General determined that the ongoing upsurge of mpox continues to constitute a public health emergency of international concern, following the fourth meeting of the International Health Regulations Emergency Committee on 5 June 2025.
Situation report in full [https://www.who.int/publications/m/item/multi-country-outbreak-of-mpox–external-situation-report–54—27-june-2025]
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