(AGENPARL) – mar 11 giugno 2024 *Source: *Tokyo Institute of Technology
*Immediate release: *June 11, 2024
*Headline:*Fixing Excess Carbon Dioxide: Biocatalyst-Driven Carboxylation
Under Mild Conditions
*Sub-headline: *Researchers achieved carboxylation of an unnatural
compound as well as natural one by utilizing Thermoplasma acidophilum malic
enzyme.
(June 11, Tokyo) Carbon capture and utilization technologies for the
conversion of carbon dioxide into carboxylic acids have garnered attention
recently, with researchers from Tokyo Tech recently demonstrating a
biocatalyzed carboxylation reaction of not only natural substrate,
pyruvate, but also unnatural one, 2-ketoglutarate, using *Thermoplasma
acidophilum* NADP+ – malic enzyme under mild reaction conditions. The
proposed strategy can be tailored for the selective synthesis through
carbon dioxide fixation reactions.
For more information, please visit the Eurekalert! news that we posted at
https://www.titech.ac.jp/english/news/2024/069389.
*Contact: *Emiko Kawaguchi, Public Relations Department, Tokyo Institute
*About Tokyo Institute of Technology*
Tokyo Tech stands at the forefront of research and higher education as the
leading university for science and technology in Japan. Tokyo Tech
researchers excel in fields ranging from materials science to biology,
computer science, and physics. Founded in 1881, Tokyo Tech hosts over
10,000 undergraduate and graduate students per year, who develop into
scientific leaders and some of the most sought-after engineers in industry.
Embodying the Japanese philosophy of “monotsukuri,” meaning “technical
ingenuity and innovation,” the Tokyo Tech community strives to contribute
to society through high-impact research.
https://www.titech.ac.jp/english/