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Why too much DNA repair can injure tissue

(AGENPARL) – Worcester (Massachusetts), mar 12 febbraio 2019 (Massachusetts Institute of Technology) MIT researchers have discovered how overactive DNA repair systems can lead to retinal damage and blindness in mice. A DNA repair enzyme called Aag glycosylase becomes hyperactive, provoking an inflammatory response that produces necrosis, leading to severe tissue damage.

Fonte/Source: https://www.eurekalert.org/pub_releases/2019-02/miot-wtm021119.php

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