(AGENPARL) – LONDON (UNITED KINGDOM), lun 19 ottobre 2020
Products containing probiotics are targeted at healthy or at-risk individuals as a preventative measure to minimise disease risk. Most studies assessing the efficacy of probiotics in humans include a mixture of healthy and unhealthy populations, while studies that focus on female populations only are largely limited to those who are pregnant or with a health condition. Pre-conception is a significant time-point during the life-course, and benefits to the health status of the woman during this period may also positively impact potential future offspring. The objective of this review is to assess the effect of probiotics administered in capsule formulation on metabolic and immune markers in healthy, non-pregnant women of reproductive age. This review followed the PRISMA guidelines. Pubmed, EMBASE, CINAHL, and Web of Science were search for relevant studies. English language articles relating to randomised-controlled trials were included. Five papers were identified with review relevant outcomes. The analysis of these papers did not find conclusive evidence for the effect of probiotic capsule supplementation on these outcomes in this healthy population. This study highlights that there is a need for research to be carried out in women during the pre-conception period on the role of probiotics to improve metabolic and immune health.
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