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LABEL-FREE FLUORESCENCE DETECTION OF PROTEIN–LIGAND INTERACTIONS BASED ON BINDING-INDUCED ENZYMATIC CLEAVAGE PROTECTION

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(AGENPARL) – LONDON (UNITED KINGDOM), lun 19 ottobre 2020 Due to significant roles in cellular functions and cancer treatments, the development of efficient methods to monitor protein–ligand interactions is essential. Herein, we developed a highly selective fluorescence strategy for protein activity detection using a ligand-modified DNA and nucleic acid dye......

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