Agenparl

fluorescence

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LABEL-FREE FLUORESCENCE DETECTION OF PROTEIN–LIGAND INTERACTIONS BASED ON BINDING-INDUCED ENZYMATIC CLEAVAGE PROTECTION

Redazione
(AGENPARL) – LONDON (UNITED KINGDOM), lun 19 ottobre 2020 Due to significant roles in cellular functions and cancer treatments, the development of efficient methods to monitor protein–ligand interactions is essential. Herein, we developed a highly selective fluorescence strategy for protein activity detection using a ligand-modified DNA and nucleic acid dye......
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PYRAZOLOANTHRONE-FUNCTIONALIZED FLUORESCENT COPOLYMER FOR THE DETECTION AND RAPID ANALYSIS OF NITROAROMATICS

Redazione
(AGENPARL) – LONDON (UNITED KINGDOM), gio 01 ottobre 2020 The development of sensors for rapid detection of chemical explosives with high sensitivity and selectivity is the focus of many research groups. In this work, we have developed a simple and straight forward synthesis of a block (co)polymer functionalized with pyrazoloanthrone......
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A COUMARIN EMBEDDED HIGHLY SENSITIVE NITRIC OXIDE FLUORESCENT SENSOR: KINETIC ASSAY AND BIO-IMAGING APPLICATIONS

Redazione
(AGENPARL) – LONDON (UNITED KINGDOM), gio 01 ottobre 2020 Fluorescence spectroscopy is a significant bio-analytical technique for specific detection of Nitric Oxide (NO) and to broadcast the in vitro and in vivo biological activities of this gasotransmitter. Herein, a benzo-coumarin embedded smart molecular probe (BCM) is employed for NO sensing......
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SMALL ORGANIC MOLECULE-BASED NANOPARTICLES WITH RED/NEAR-INFRARED AGGREGATION-INDUCED EMISSION FOR BIOIMAGING AND PDT/PTT SYNERGISTIC THERAPY

Redazione
(AGENPARL) – LONDON (UNITED KINGDOM), mer 30 settembre 2020 Organic nanomaterials with efficient ROS generation and high photothermal conversion efficiency have emerged as a new generation of therapeutic agents for PDT/PTT synergistic cancer treatment. However, most of the organic nanomaterials exhibited weak emission in water because of the aggregation-caused quenching......
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CU2+-REGULATED REVERSIBLE COORDINATION INTERACTION OF GQDS@TB/GMP ICP NANOPARTICLES: TOWARDS DIRECT MONITORING CEREBROSPINAL ACETYLCHOLINESTERASE AS A BIOMARKER FOR CHOLINIC BRAIN DYSFUNCTION

Redazione
(AGENPARL) – LONDON (UNITED KINGDOM), lun 28 settembre 2020 This work demonstrates a new strategy for sensing of cerebrospinal acetylcholinesterase (AChE) as a cholinergic biomarker for brain dysfunction based on graphene quantum dots (GQDs) functionalized lanthanide infinite coordination polymer (Ln-ICP) nanoparticles. The ICPs used in this work are comprised of......
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A NOVEL QUINOLINYL-TETRAPHENYLETHENE BASED FLUORESCENCE “TURN-ON” SENSOR FOR ZN2+ WITH A LARGE STOKES SHIFT AND ITS APPLICATIONS FOR PORTABLE TEST STRIPS AND BIOLOGICAL IMAGING

Redazione
(AGENPARL) – LONDON (UNITED KINGDOM), lun 28 settembre 2020 A new 8-hydroxyquinoline derivative bearing the hydroxytetraphenylethene moiety called TPE(OH)-8HQ has been designed, synthesized and evaluated as an efficient fluorescence “turn-on” sensor for detection of Zn2+ based on chelation-enhanced fluorescence (CHEF) mechanism in neutral aqueous solution. The free sensor displays a......
Agenparl English Educazione Scienza e Tecnologia Social Network

SELECTIVITY AND BIO-COMPATIBILITY OF SELF-ASSEMBLED CHIRAL FLOWER-LIKE AND HELICAL NANOSTRUCTURES

Redazione
(AGENPARL) – LONDON (UNITED KINGDOM), sab 26 settembre 2020 The molecular building block NDI-LCA was synthesized by substitution of NDA at di-imide position with two lithocholic acid moieties. It was found that the NDI-LCA conjugate exhibits good thermal stability. The photophysical such as UV-vis and fluorescence spectral measurements and theoretical......
Agenparl English Educazione Scienza e Tecnologia Social Network

A NEAR-INFRARED FLUORESCENCE PROBE FOR IMAGING OF PANTETHEINASE IN CELLS AND MICE IN VIVO

Redazione
(AGENPARL) – LONDON (UNITED KINGDOM), ven 25 settembre 2020 Pantetheinase is an amidohydrolase that cleaves pantetheine into pantothenic acid and cysteamine. Functional studies have found that ubiquitous expression of this enzyme is associated with many inflammation diseases. However, the lack of near-infrared fluorescence probes limits the better understanding of the......
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A MULTI-PHOTON FLUORESCENT PROBE BASED ON QUINOLINE GROUPS FOR HIGHLY SELECTIVE AND SENSITIVE DETECTION OF LIPID DROPLETS

Redazione
(AGENPARL) – LONDON (UNITED KINGDOM), gio 24 settembre 2020 Compared to general fluorescent probes, multi-photon fluorescent probes behave deeper tissue penetration, lower auto-fluorescence and lower photo-toxicity in bio-imaging field. Herein, we synthesized a series multi-photon fluorescent probe (L1 ~ L3) based on quinolone groups. Of notably, the three-photon fluorescence of......
Agenparl English Bandi Educazione Lavoro Scienza e Tecnologia Social Network

RESEARCHER IN REMOTE SENSING OF SUN-INDUCED FLUORESCENCE (M/F)

Redazione
(AGENPARL) – ESCH -ALZETTE (LUXEMBOURG), mer 23 settembre 2020 Type: ResearcherContract type: Permanent contractPlace: Belvaux Context Your work environment The Luxembourg Institute of Science and Technology (LIST) is a Research and Technology Organization (RTO) active in the fields of materials, environment and IT. By transforming scientific knowledge into technologies, smart......

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